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Several papers point to a preservation or increase in lean body mass.21 One even showed improvements in muscle composition (a decrease in muscle fat) in non-diabetic participants.27 Others have seen a reduction of lean body mass, making up around 20-50% of total weight lost, but its important to note that this was a review of research into several anti-diabetic drugs including some that arent GLP-1 RAs.26 Research into low-calorie diets reveals that exercise and a high protein intake can help preserve muscle mass and even build muscle while restricting calories, so you cant just eat junk, not exercise, and still expect these drugs to work miracles.22 Your overall health can improve by adding exercise and a healthy, protein-rich diet to a GLP-1 RA routine

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Research into BPC-157 wound healing effects at the hepatic level aligns with its broader anti-inflammatory and angiogenic mechanisms, and the findings have generated interest in the context of drug-induced liver injury and alcohol-related liver disease both conditions with significant unmet clinical need

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doi: 10.2337/dc25-S002 11 HermanRJHayesMRAudrain-McGovernJAshareRLSchmidtHD